1.
During
which phase of the meiotic cell cycle does DNA replication occur?
a.
Interphase
b.
Prophase
c.
Metaphase
d.
Anaphase
e.
Telophase
2.
Replication
a.
DNA
à
Protein
b.
DNA
à
RNA
c.
RNA
à
Protein
d.
DNA
à
DNA
3.
The
notations P and p ( or any upper case and lower case letters) in genetics
problems represent
a.
Phenotype
of an individual
b.
Separate
genes
c.
Individual
alleles
d.
Chromosome
mutations
4.
Repeated
DNA sequences on the ends of eukaryotic chromosomes are
a.
Introns
b.
Exons
c.
Telomeres
d.
Isomeres
5.
During
which phase of meiosis does the nuclear membrane reform around chromosomes
a.
Interphase
b.
ProphaseI
c.
Metaphase
II
d.
Anaphase
I
e.
TelophaseII
6.
If
a tRNA has anticodon UUU it carries amino acid
a.
Glycine
b.
Serine
c.
Phenylalanine
d.
Lysine
7.
Which
indicates a homozygous genotype?
a.
AB
b.
Aa
c.
BB
d.
Ab
8.
Homologous
chromosomes move towards opposite poles of a dividing cell during…
a.
Mitosis
b.
Meiosis
I
c.
Meiosis
II
d.
Fertilization
e.
Binary
Fission
9.
A
gene that interferes with another gene is
a.
Polygenic
b.
Epistatic
c.
Pleiotroipic
d.
Dominant
10. Where is the
codon
a.
rRNA
b.
mRNA
c.
tRNA
11. Meiosis II is
similar to mitosis in that…
a.
Homologous
chromosomes synapse
b.
DNA
replicates before the division
c.
The
daughter cells are diploid
d.
Sister
chromatids separate during anaphase
e.
The
chromosome number is reduced
12. In humans
brown eyes are dominant over blue eyes. A brown-eyed woman who has a blue-eyed
child has the genotype
a.
bb
b.
Bb
c.
BB
d.
None
of these are correct
e.
Not
able to determine from info given
13. mRNA is
synthesized by
a.
RNA
Polymerase I
b.
DNA
Ligase
c.
DNA
Polymerase
d.
RNA
Polymerase II
14. How many
nucleotides code for an amino acid
a.
2
b.
3
c.
4
d.
1
15. DNA
replication is
a.
Conservative
b.
Semiconservative
c.
Dispersive
16. Metaphase of
meiosis I & meiosis II differ in that…
a.
Chromosomes
line up at the equator
b.
Homologues
line up in meiosis I and duplicated chromosomes line up in meiosis II
c.
Sister
chromatids line up in meiosis I and chromosomes line up in meiosis II
d.
There
are the same number of chromosomes
17. Infected mice
with strains of streptococcus
a.
TH
Morgan
b.
Walter
Sutton
c.
Frederick
Griffith
d.
Avery,
MacLeod, McCarty
18. Transcription
a.
DNA
à
Protein
b.
DNA
à
RNA
c.
RNA
à
Protein
d.
DNA
à
DNA
19. If 25% of the
offspring of one set of parents show the recessive phenotype, the parents were
probably
a.
Both
homozygous recessive
b.
Both
homozygous dominant
c.
Both
heterozygous
d.
One
homozygous dominant, one homozygous recessive
20. At which stage
of meiosis do chromatids separate and become daughter chromosomes?
a.
Metaphase
I
b.
Anaphase
I
c.
Metaphase
II
d.
Anaphase
II
e.
Telophase
II
21. Where is the
anticodon
a.
rRNA
b.
mRNA
c.
tRNA
22. The inheritance
of blood types in humans can be explained by
a.
Epistasis
b.
Linked
genes
c.
Co-dominance
d.
Incomplete
dominance
23. Sickle cell
Anemia is caused by
a.
Frameshift
mutation
b.
Deletion
c.
Translocation
d.
Point
mutation
24. A human cell
containing 44 autosomes and two X chromosomes is…
a.
A
somatic cell of a male
b.
A
zygote
c.
A
somatic cell of a female
d.
A
sperm cell
e.
An
egg cell
25. T/F - A 1:2:1
ratio describes the genotype which arises from a monohybrid cross of two
heterozygous individuals
26. A _____ is the
complete set of chromosomes of an organism, arranged and displayed in pairs and
ordered by size
a.
Genome
b.
Karyotype
c.
Nucleus
heredity
d.
Gene
27. An allele that
codes for more than one characteristic is
a.
Polygenic
b.
Epistatic
c.
Pleiotropic
d.
Dominant
28. mRNA is
synthesized from
a.
DNA
template strand
b.
RNA
protein strand
c.
DNA
coding strand
29. A mutation
that creates a stop codon is a
a.
Transversion
b.
Nonsense
mutation
c.
Frame
shift mutation
d.
Missense
mutation
30. Which 2 cells
would be more genetically similar to each other
a.
Two
gametes produced by the same person
b.
Two
somatic cells produced by the same person
c.
Two
eggs produced by the same woman
d.
Two
sperm produced by the same man
31.
Found that transforming material is DNA
a.
TH
Morgan
b.
Walter
Sutton
c.
Frederick
Griffith
d.
Avery,
MacLeod, McCarty
32.
Which blood type would not be possible for children of a type AB
mother and a type A father
a.
O
b.
A
c.
B
d.
AB
33.
Non-coding regions of the mRNA are called
a.
Exons
b.
Mutations
c.
Introns
d.
All parts of the mRNA code for the protein
34.
Crossing over usually contributes to genetic variation by
exchanging chromosomal segments between
a.
Sister chromatids of a chromosome
b.
Chromatids of nonhomologues
c.
Nonsister chromatids of homologues
d.
Nonhomologous loci of the genome
e.
Autosomes and sex chromosomes
35. An extra
finger in humans is rare but is due to a dominant gene. When one parent is
normal and the other parent has an extra finger but is heterozygous for the
trait, what is the probability that the first child will be normal?
a.
0%
b.
25%
c.
50%
d.
75%
36. T/F – The
central dogma of molecular biology states that information flows in one
direction DNA à RNA à Protein
37. Discovered
mutant white eye in drosophila
a.
TH
Morgan
b.
Walter
Sutton
c.
Frederick
Griffith
d.
Avery,
MacLeod, McCarty
38. A single
glitch in the DNA base pairs is
a.
Nondisjunction
b.
Deletion
c.
Translocation
d.
Point
mutation
39. Match the
following: (a-f) with (g-l)
a.
Fertilization
b.
Asexual
reproduction
c.
Interphase
d.
Crossing
Over
e.
Sperm
f.
Ovum
g.
Sperm
and egg cell join
h.
Exchange
of genes between pairs of homologous chromosomes
i.
Female
egg
j.
All
copies of the single parent’s genes are passed to the offspring
k.
Time
between cell divisions
l.
Male
gamete
40. Carriers of
the color-blindness trait include
a.
Men
heterozygous for the trait
b.
Men
homozygous for the trait
c.
Women
heterozygous for the trait
d.
Women
homozygous for the trait
41. How many
chromosomes are in the somatic cells of an organism that has a haploid number
of 8?
a.
8
b.
16
c.
4
d.
32
42. This type of
RNA is involved in Translation
a.
mRNA
b.
rRNA
c.
tRNA
d.
More
than one answer is correct
43. A pedigree
chart shows
a.
The
genotypic ratios of the offspring
b.
Types
of gametes produced by parents
c.
The
pattern of inheritance of a specific gene
d.
Which
genes are co-dominant
e.
The
genotypes of any parents
44. In humans,
gametes contain
a.
1
autosome and 45 sex chromosomes
b.
1
autosome and 22 sex chromosomes
c.
45
autosomes and 1 sex chromosome
d.
22
autosomes and 1 sex chromosome
45. Key: for the
next 4 questions: a= all the offspring will exhibit the dominant trait, b= all
the offspring will exhibit the recessive trait, c= the recessive trait will
show up in about 50% of the offspring, d= the dominant trait will show up in
about 75% of the offspring. What will
be the result if
a.
Bb
mates with bb
b.
BB
mates with bb
c.
bb
mates with bb
d.
Bb
mates with Bb
46. DNA is
synthesized by
a.
RNA
Polymerase I
b.
DNA
Ligase
c.
DNA
Polymerase
d.
RNA
Polymerase II
47. Trisomy is
caused by
a.
Nondisjunction
b.
Deletion
c.
Translocation
d.
Point
mutation
48. In Telophase
II, cytokinesis results in
a.
Two
diploid cells
b.
Four
haploid cells
c.
Four
diploid cells
d.
Two
haploid cells
49. The rule of
multiplication vs. the Rule of addition
50. A mutation
that causes part of a chromosome to be moved to a new location is
a.
Inversion
b.
Duplication
c.
Translocation
d.
Deletion
51. Translation
a.
DNA
à
Protein
b.
DNA
à
RNA
c.
RNA
à
Protein
d.
DNA
à
DNA
52. Crossing-over
occurs
a.
During
prophase I
b.
At
the centromere
c.
During
fertilization
d.
During
prophase II
53. In a testcross
genotype is determined by
a.
A
homozygous dominant genotype is crossed with a heterozygote
b.
A
dominant phenotype is crossed with a heterozygote
c.
A
recessive phenotype is crossed with a dominant phenotype
d.
A
recessive phenotype is crossed with a heterozygote
54. DNA
replication occurs
a.
In
both meiosis I and meiosis II
b.
When
the chromosomes align at the cells equator
c.
Prior
to prophase I
d.
After
Telophase I
55. Multiple genes
involved in controlling a single characteristic
a.
Polygenic
b.
Epistasis
c.
Pleiotropic
d.
Dominant
56. Homologous
chromosomes are closely associated with each other in ___ by proteins called
____
57. This organelle
is responsible for removing non-coding regions of the mRNA
a.
Spliceosome
b.
Lysosome
c.
Vessicle
d.
Nucleoid
58. The chiasmata
is the
a.
Protein
that holds homologues together
b.
Site
of DNA replication
c.
Site
of crossing over
d.
A
phase of meiosis
59. Point
mutations are also called
a.
Base
substitutions
b.
Chromosomal
aberrations
c.
Frame
shift mutations
d.
Missense
mutations
e.
More
than one answer is correct
60. The
chromosomal theory of inheritance
a.
TH
Morgan
b.
Walter
Sutton
c.
Fredrick
Griffith
d.
Avery,
MacLeod, McCarty
